(Science - Genome) Annotation of the Celera Human Gene Assembly
With the acclaimed unraveling of the structure of DNA in the 1950's, by the 1980's there was a push to perhaps document the entire genome of a human being, all 3.2 billion base pairs. It was a tedious process to use Peter Sanger's method to construct the genome of even something small, but it was accurate. A bacteria could take you years to identify each of the thousands of base pairs. But the information gleaned and the potential for mankind was too strong. So in 1990 an array of 20 international laboratories set out to completely annotate the genome of humans in fifteen years, an aggressive schedule that would use 3 billion in public funding and would report their findings within 24 hours.
But this was also the era of growing computer capacity, accelerating processing speeds, decreasing costs and the time of growing momentum for Silicon Valley and venture capital investing in solutions. Seven years before the completion of the international Human Genome Project, a private company, Celera, brought a radical approach and newly designed machines that could automate the process. The race was on.
In the end, both the Human Genome Project and Celera finished at about the same time, working to publish the discovery jointly. But prior to the completion, and nearing the finish line, Celera printed this large format chart to illustrate the project at almost 90% completion.
This large printed chart documents one of man's greatest accomplishments, as he now understand the individual components which make him unique. It may be the last time the majority of the Human Genome is printed in one place, as even at the bottom of this vast chart are online URL addresses by which you can view individual sequences.
And thanks to Moore's law, what cost nations 3 billion dollars to complete in just over a decade to do can be done for any individual for $100 and just a few weeks.
At the time of its reveal and presentation President Bill Clinton discussed how Thomas Jefferson at one time reviewed the map of Lewis and Clark and how it "defined the contours and expanded the frontiers of our continent and our imagination", but this map of the human genome was the "most important and most wonderous map ever produced by human kind".
Condition is very good. Size is approximately 55.75 x 38.5 (inches)